Odd behaviour with Windows 10

Hi,

I am having an odd problem.  I have parts of my suite running on different client machines.  I am using jenkins to control the running of the different parts of the suite.  I am calling testexecute from the command line and this was and is working on most of the test machines except for 3 now, 3 of the 6 windows 10 machines.  We are testing a click once application, so the first thing we are doing is hitting the URL to launch the application.  on the 3 suspect machines, I see test execute start, and i see it hit the URL, but then we do not get the application starting.  The next level oddity is if i go onto the client, and manually open a command prompt and run the exact same command, everything works. 

Does anyone have any idea why this might be happening?

Thanks