Looping the execution of a test, using a different spreadsheet data source each iteration?

We have a need to verify data via the GUI of our application with changed customer data contained in Excel Spreadsheets.  We will get dozens to hundreds of these spreadsheets per month, each from an individual customer.

Is it possible to set up any test script to loop iterations, but grab a different spreadsheet file each iteration.  Obviously, there would need to be a master file list or some config file that tells the script which files to use, or the like.

Thanks in advance for any assistance you can provide.