I'm not familiar with this particular language personally, but I would assume it would down to what it is using to present the UI. Perhaps signing up for / downloading trial would be a good start. You could also open up a discussion directly with SmartBear.
I'm with cunderw... I'm not familiar with Small Talk so I can't speak from direct experience. My suspicion is that there will be some limitations of what TestComplete can do with regards to applications written in Small Talk. You may still be able to use TestComplete but just not as an "Open" application.
Your best bet is to download the trial as recommended and see what happens.
