UPDATE***
I have tracked down what my issue is. FOR ANYONE seeing the Red rectangle of death on the full browser window:
I was using remote desktop to work on a scripting box that I do ALL of my ui testing on, so it doesn't destroy my local things. 12.5 with chrome, will not function this way. If I access the machine directly and run the exact same test, no problems. All other browsers work through Remote Desktop Connection.. 12.42 worked just great this way as well with all browsers, including chrome. So my question for the devs is, what changed with how we interact with chrome and 12.5?