1. Yes, you can. Here's a usage reference, but whenever you find a coding reference in the documentation, there will be a Python example included.
https://support.smartbear.com/testcomplete/docs/scripting/specifics/python.html
2. Wildcards will be helpful in the cases where objects may change frequently.
https://support.smartbear.com/testcomplete/docs/reference/misc/using-wildcards.html
3. Here is the beginning of the desktop testing reference https://support.smartbear.com/testcomplete/docs/app-testing/desktop/index.html
