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Yes, that can be achieved using external properties.
SoapUI allows properties file, to be placed under SOAPUI_HOME/bin, with soapui.properties name. When SoapUI is started, properties gets automatically loaded.
TimeOut: Assuming that it is used for the assertions. Define this in above mentioned property file. And use property expansion instead of hard code value where it needs to be used, say ${#Project#TIME_OUT}
Endpoint: Go to service interface (which you see when wsdl is added to the project), go to Service Endpoints tab and define ${#Project#SERVICE1_ENDPOINT} and click on assign to all test cases. Make sure SERVICE1_ENDPOINT is defined in above mentioned property file.
You may see screen shots 2,3 of Section #4. of http://www.soapui.org/functional-testing/properties/working-with-properties.html