Does SoapUI do stuff in the db or just stub it?

When I send a request via SoapUI (or actually use LoadUI to hit a SoapUI test case) does it actually do stuff in the underlying database or as some other testing tools do, just 'stub' it?

This is important as I have a number of SoapUI tests that need running, that may need running in a particular order if it actually does stuff in the db. It dictates whether I can use static data in the repeated requests I make via LoadUI or if I need values from data files to be read in each time a request is made.

Is there a preference that can be set to do either?