Yes It is.
There are many ways
You can use DataSourse and DataSource loop components (SoapUI Pro only), for sleeping can be used "Delay".
http://www.soapui.org/userguide/functional/datasourcestep.htmlAlso you can use "Conditional Goto" step for creating loop.
You can connect to excel from groovy (import java.xls*)
For inserting to request parameters, can be used "Property transfer", or generete XML by Groovy Script.
As I said, there are many ways, but I think groovy script must be used for all variants.