Chrome is not able to identify object in frame

I run the script on the webapplication that is developed using frame. IE is able to identify the object in the frame but not Chrome. I have set the following at the beginning of the test and still it does not fix the problem.

Browsers.Item("chrome").RunOptions= "--allow-file-access-from-files --disable-web-security";
Browsers.Item("chrome").Run();

I look into the Browser Explorer, the frame shows as one panel, there isn't break down in that panel whereas IE do.

Any idea how to fix this problem?