HttpHostConnectException: Connection to http://myserver.com refused

I'm getting these connection timeouts using the latest maintenance version of SoapUI (not Pro).  I tried changing the preferences HTTP settings timeout value to a really high number, but it doesn't seem to be using that value.  I also set it to zero and got the same results.

Fri Feb 20 10:02:29 EST 2015:ERROR:org.apache.http.conn.HttpHostConnectException: Connection to http://myserver.com refused
   org.apache.http.conn.HttpHostConnectException: Connection to http://myserver.com refused
    at com.eviware.soapui.impl.wsdl.support.http.SoapUIMultiThreadedHttpConnectionManager$SoapUIClientConnectionOperator.openConnection(SoapUIMultiThreadedHttpConnectionManager.java:332)
    at org.apache.http.impl.conn.AbstractPoolEntry.open(AbstractPoolEntry.java:149)
    at org.apache.http.impl.conn.AbstractPooledConnAdapter.open(AbstractPooledConnAdapter.java:121)
    at org.apache.http.impl.client.DefaultRequestDirector.tryConnect(DefaultRequestDirector.java:561)
    at org.apache.http.impl.client.DefaultRequestDirector.execute(DefaultRequestDirector.java:415)
    at org.apache.http.impl.client.AbstractHttpClient.execute(AbstractHttpClient.java:820)
    at org.apache.http.impl.client.AbstractHttpClient.execute(AbstractHttpClient.java:754)
    at com.eviware.soapui.impl.wsdl.support.http.HttpClientSupport$Helper.execute(HttpClientSupport.java:247)
    at com.eviware.soapui.impl.wsdl.support.http.HttpClientSupport.execute(HttpClientSupport.java:362)
    at com.eviware.soapui.impl.wsdl.submit.transports.http.HttpClientRequestTransport.submitRequest(HttpClientRequestTransport.java:324)
    at com.eviware.soapui.impl.wsdl.submit.transports.http.HttpClientRequestTransport.sendRequest(HttpClientRequestTransport.java:237)
    at com.eviware.soapui.impl.wsdl.WsdlSubmit.run(WsdlSubmit.java:127)
    at com.eviware.soapui.impl.wsdl.WsdlSubmit.submitRequest(WsdlSubmit.java:80)
    at com.eviware.soapui.impl.wsdl.WsdlRequest.submit(WsdlRequest.java:242)
    at com.eviware.soapui.impl.wsdl.teststeps.WsdlTestRequestStep.run(WsdlTestRequestStep.java:419)
    at com.eviware.soapui.impl.wsdl.support.AbstractTestCaseRunner.runTestStep(AbstractTestCaseRunner.java:239)
    at com.eviware.soapui.impl.wsdl.testcase.WsdlTestCaseRunner.runCurrentTestStep(WsdlTestCaseRunner.java:52)
    at com.eviware.soapui.impl.wsdl.support.AbstractTestCaseRunner.internalRun(AbstractTestCaseRunner.java:152)
    at com.eviware.soapui.impl.wsdl.support.AbstractTestCaseRunner.internalRun(AbstractTestCaseRunner.java:47)
    at com.eviware.soapui.impl.wsdl.support.AbstractTestRunner.run(AbstractTestRunner.java:139)
    at java.util.concurrent.Executors$RunnableAdapter.call(Executors.java:471)
    at java.util.concurrent.FutureTask.run(FutureTask.java:262)
    at java.util.concurrent.ThreadPoolExecutor.runWorker(ThreadPoolExecutor.java:1145)
    at java.util.concurrent.ThreadPoolExecutor$Worker.run(ThreadPoolExecutor.java:615)
    at java.lang.Thread.run(Thread.java:745)
   Caused by: java.net.ConnectException: Connection timed out
    at java.net.PlainSocketImpl.socketConnect(Native Method)
    at java.net.AbstractPlainSocketImpl.doConnect(AbstractPlainSocketImpl.java:339)
    at java.net.AbstractPlainSocketImpl.connectToAddress(AbstractPlainSocketImpl.java:200)
    at java.net.AbstractPlainSocketImpl.connect(AbstractPlainSocketImpl.java:182)
    at java.net.SocksSocketImpl.connect(SocksSocketImpl.java:363)
    at java.net.Socket.connect(Socket.java:579)
    at org.apache.http.conn.scheme.PlainSocketFactory.connectSocket(PlainSocketFactory.java:123)
    at com.eviware.soapui.impl.wsdl.support.http.SoapUIMultiThreadedHttpConnectionManager$SoapUIClientConnectionOperator.openConnection(SoapUIMultiThreadedHttpConnectionManager.java:310)
    ... 24 more